July 14^th- 25^th July 2017

Department of Clinical and Experimental Medicine

University of Pisa, Pisa

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Muscle fatigue is the decline in ability of a muscle to generate force. It can be a result of vigorous exercise but abnormal fatigue may be caused by barriers to or interference with the different stages of muscle contraction.

Fatigue is a complex problem, since multiple factors are clearly involved.

The aim of the course will be to provide the state of the art and cutting-edge developments in knowledge and clinical approach of exercise training and muscle fatigue in healthy subjects and in patients with neuromuscular disease.

The course will highlight research findings related to fatigue in main neuromuscular disorders, approaching both the methological issues and clinical applications of more recent achievements on pathophysiology, diagnosis and treatment of this important manifestation of functional muscle impairment.

The program is organized in thematic sections within each of them divided in didactive lessons and pratical sections illustrating the applications of the topics.

PROGRAM

JULY 14 –FRIDAY

H 15-17

Introduction

Lecture: “Muscle exercise: from health to disease” Prof Corrado Angelini (Venezia)

Introduction: Prof. Gino Santoro (Pisa)

Welcome cocktail

JULY 15- SATURDAY

H 9-13

Skeletal muscle: structure, function and effect of exercise in normal conditions

Coordinator: Riccardo Ruffoli (Pisa)

JULY 17, MONDAY

H 9-13

Inside the mechanisms of muscle remodelling

Coordinator: Marco Gesi (Pisa)

H 15-18

Muscle training: strategies in healthy people

Coordinator: Fabio Galetta (Pisa)

JULY 18, TUESDAY

Skeletal muscle fatigue

H 9-13

Coordinator: Giuseppe D’Antona (Pavia)

JULY 19, WEDNESDAY

H 9-13

Clinical assessment of muscle fatigue in muscle diseases

Gabriele Siciliano (Pisa)

H 15-18

Laboratory investigations to study muscle fatigue

Michelangelo Mancuso (Pisa)

JULY 20, THURSDAY

H 9-13

Muscle diseases

Coordinator: Giulia Ricci (Pisa)

JULY 21, FREEDAY

H 9-13

Neurogenic diseases

Coordinator: Elena Caldarazzo Jenco (Pisa)

H 15-18

Exercise and fatigue in muscle diseases

Coordinator: Massimiliano Filosto (Brescia)

JULY 22, SATURDAY

H 9-13

Overtraining: clinical and molecular correlates

Coordinator: Ferdinando Franzoni (Pisa)

JULY 24, MONDAY

H 9-13

Aging and sarcopenia

Coordinator: Fabio Monzani (Pisa) 

H 15-18

Diet and exercise, supplements and doping

Coordinator: Angelo Pizzi (Pisa)

JULY 25, TUESDAY

H 9-13

Discussion of case reports

Cordinators: Gabriele Siciliano, Ferdinando Franzoni

Learning questionnaire